Antimicrobial, Antioxidant and Cytotoxic Potential of Aerial Parts of Monotheca buxifolia
| Autor: | Farhat Amin, Ghusia Lutfullah, Muhammad Rafiq, Asma Shah, Alam Khan, Sajjad Ahmad, Muhammad Saleem Khan, Maimoona Gull, Noreen Azhar, Faiz Ullah Khan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0106 biological sciences
Antifungal Antioxidant antioxidant medicine.drug_class General Mathematics medicine.medical_treatment General Physics and Astronomy 01 natural sciences Median lethal dose General Biochemistry Genetics and Molecular Biology cytotoxic medicine Cytotoxic T cell Monotheca buxifolia lcsh:Science lcsh:Science (General) Multidisciplinary biology Traditional medicine Chemistry food and beverages General Chemistry General Medicine Acinetobacter Antimicrobial biology.organism_classification 0104 chemical sciences 010404 medicinal & biomolecular chemistry antibacterial General Earth and Planetary Sciences lcsh:Q Artemia salina General Agricultural and Biological Sciences antifungal 010606 plant biology & botany lcsh:Q1-390 |
| Zdroj: | Journal of Mathematical and Fundamental Sciences, Vol 51, Iss 2, Pp 138-151 (2019) |
| ISSN: | 2338-5510 2337-5760 |
| Popis: | In this study, different aerial parts of Monotheca Buxifolia were screened for their antibacterial, antifungal, and anti-oxidant activity . Extract of the fruit was most active against P. mirabilis, MSSA and M. morganii strains. Moreover, the methanolic fruit extract demonstrated good antibacterial properties against VRSA, S. aureus and Acinetobacter . Despite having good antibacterial properties, Monotheca buxifolia showed low antifungal activity. The cytotoxic activity was the highest in the pet-ether fruit extract, causing 60% of lethality against Artemia salina larvae with LD 50 at 3.307. The highest scavenging activity was shown by the methanolic leaf extract in a concentration-dependent pattern. The findings of this study suggest that Monotheca Buxifolia has good antibacterial, antioxidant potential but low antifungal properties. |
| Databáze: | OpenAIRE |
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