Solubility and Chemistry of Materials Encountered by Beryllium Mine and Ore Extraction Workers
| Autor: | Abigail Rudd, Wenjie Huang, David C. Deubner, Diego P. Fernandez, Rod Larson, Philip Sabey, Jason Storrs, William P. Johnson |
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| Rok vydání: | 2011 |
| Předmět: |
Beryllium exposure
chemistry.chemical_element Air Pollutants Occupational Mining Berylliosis chemistry.chemical_compound Risk Factors Aluminium Occupational Exposure Hypersensitivity Humans Lymphocytes Solubility Dissolution Cells Cultured Cell Proliferation Metallurgy Extraction (chemistry) Public Health Environmental and Occupational Health respiratory tract diseases Beryllium hydroxide Occupational Diseases chemistry Aluminum Silicates Beryllium Beryllium Disease |
| Zdroj: | Journal of Occupational & Environmental Medicine. 53:1187-1193 |
| ISSN: | 1076-2752 |
| DOI: | 10.1097/jom.0b013e31822cfe38 |
| Popis: | OBJECTIVE Beryllium mine and ore extraction mill workers have low rates of beryllium sensitization and chronic beryllium disease relative to the level of beryllium exposure. The objective was to relate these rates to the solubility and composition of the mine and mill materials. METHOD Medical surveillance and exposure data were summarized. Dissolution of BeO, ore materials and beryllium hydroxide, Be(OH)(2) was measured in synthetic lung fluid. RESULT The ore materials were more soluble than BeO at pH 7.2 and similar at pH 4.5. Be(OH)(2) was more soluble than BeO at both pH. Aluminum dissolved along with beryllium from ore materials. CONCLUSION Higher solubility of beryllium ore materials and Be(OH)(2) at pH 7.2 might shorten particle longevity in the lung. The aluminum content of the ore materials might inhibit the cellular immune response to beryllium. |
| Databáze: | OpenAIRE |
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