¿Es la infección urinaria post-litotricia factor agravante del daño renal de dicha terapia?
| Autor: | Savvas Paraskevopoulos, Demetrios Radopoulos, Ioannis Vakalopoulos |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
medicine.medical_specialty
Creatina fosfoquinasa Urology Urinary system medicine.medical_treatment Litotricia extracorpórea Hidrogenaláctica Urine Lithotripsy Infección urinaria Medicine In patient Prospective cohort study B2 microglobulina Daño renal biology business.industry Beta-2 microglobulin General Medicine Surgery Enzimas renales biology.protein Biomarker (medicine) Creatine kinase business |
| Zdroj: | Archivos Españoles de Urología (Ed. impresa) v.63 n.6 2010 SciELO España. Revistas Científicas Españolas de Ciencias de la Salud instname |
| Popis: | OBJETIVOS To prospectively assess if urinary tract infection (UTI) after extracorporeal shock wave lithothripsy (ESWL) enhances immediate renal damage in patients with renal stones. METODOS Levels of lactic dehydrogenase (LDH), creatine phosphokinase (CPK), and ?2 microglobulin were measured in the urine of 171 patients, before and after ESWL for treatment of up to 3cm renal stones. Standard investigation included urine sample before and after treatment. Patients were divided in two groups in accordance to presence of positive bacterial urine sample after ESWL. Changes in biomarker values pre- and post- ESWL were assessed via X2 test for both groups and compared between the two groups for post-treatment values. RESULTADOS Despite pre-treatment antibiotic therapy, 21.6% of the patients presented with UTI after ESWL. In the group with clear post-treatment urine samples there was a 5.8, 2.2, and 0.7 fold increase of CPK, LDH, and ?2 microglobulin levels after ESWL, respectively (p |
| Databáze: | OpenAIRE |
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