Does functional health status predict health-related quality of life in children after Fontan operation?
| Autor: | Tim Takken, Nienke Duppen, Elisabeth M. W. J. Utens, Livia Kapusta, Willem A. Helbing, Arend D. J. ten Harkel, Irene M. Kuipers, Michiel Schokking, Karolijn Dulfer, Gabriëlle G. van Iperen, Sjoerd S. M. Bossers |
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| Přispěvatelé: | Child and Adolescent Psychiatry / Psychology, Pediatrics, ACS - Amsterdam Cardiovascular Sciences, AII - Amsterdam institute for Infection and Immunity, Paediatric Cardiology |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Parents Pediatrics Health Status 030204 cardiovascular system & hematology Fontan Procedure 0302 clinical medicine Quality of life Surveys and Questionnaires Fontan circulation Medicine Prospective Studies Child Non-U.S. Gov't Netherlands Research Support Non-U.S. Gov't General Medicine Magnetic Resonance Imaging Perinatology congenital heart disease and Child Health Multicenter Study Treatment Outcome Female Cardiology and Cardiovascular Medicine Psychosocial Heart Defects Congenital medicine.medical_specialty Adolescent Heart Ventricles Functional health Research Support 03 medical and health sciences 030225 pediatrics Journal Article Humans Medical history Cognitive skill Pediatrics Perinatology and Child Health Health related quality of life business.industry Other Research Radboud Institute for Health Sciences [Radboudumc 0] Cross-Sectional Studies quality of life Multivariate Analysis Pediatrics Perinatology and Child Health Multivariate prediction Exercise Test Physical therapy business |
| Zdroj: | Cardiology in the Young, 26(3), 459-468 Cardiology in the Young, 26(3), 459–468. Cambridge University Press Cardiology in the Young, 26, 459-68 Cardiology in the Young, 26, 3, pp. 459-68 Cardiology in the Young, 26(3), 459-468. Cambridge University Press Cardiology in the young, 26(3), 459-468. Cambridge University Press |
| ISSN: | 1047-9511 |
| Popis: | PurposeIt is important to identify those children with a Fontan circulation who are at risk for impaired health-related quality of life. We aimed to determine the predictive value of functional health status – medical history and present medical status – on both physical and psychosocial domains of health-related quality of life, as reported by patients themselves and their parents.MethodsWe carried out a prospective cross-sectional multi-centre study in Fontan patients aged between 8 and 15, who had undergone staged completion of total cavopulmonary connection according to a current technique before the age of 7 years.Functional health status was assessed as medical history – that is, age at Fontan, type of Fontan, ventricular dominance, and number of cardiac surgical procedures – and present medical status – assessed with magnetic resonance imaging, exercise testing, and rhythm assessment. Health-related quality of life was assessed with The TNO/AZL Child Questionnaire Child Form and Parent Form.ResultsIn multivariate prediction models, several medical history variables, such as more operations post-Fontan completion, lower age at Fontan completion, and dominant right ventricle, and present medical status variables, such as smaller end-diastolic volume, a higher score for ventilatory efficiency, and the presence of sinus node dysfunction, predicted worse outcomes on several parent-reported and self-reportedphysicalas well aspsychosocialhealth-related quality of life domains.ConclusionsMedical history and worse present medical status not only predicted worse physical parent-reported and self-reported health-related quality of life but also worse psychosocial health-related quality of life and subjective cognitive functioning. These findings will help in identifying patients who are at risk for developing impaired health-related quality of life. |
| Databáze: | OpenAIRE |
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