Predictors of Loss to Follow-Up Among Pediatric and Adult Hematopoietic Cell Transplantation Survivors
| Autor: | Rammurti T. Kamble, Anita D'Souza, Leslie Lehmann, Kirk R. Schultz, Miguel Angel Diaz, Nandita Khera, Anita J. Kumar, Karen K. Ballen, Siddhartha Ganguly, Yachiyo Kuwatsuka, Wael Saber, Susana R. Marino, Sachiko Seo, Ruta Brazauskas, Baldeep Wirk, Shahrukh K. Hashmi, Christopher Bredeson, Yoshihiro Inamoto, Khalid Bo-Subait, Jean A. Yared, Gregory A. Hale, Navneet S. Majhail, Akshay Sharma, Harry C. Schouten, Saurabh Chhabra, Cesar O. Freytes, Jason Tay, Christopher E. Dandoy, Kehinde Adekola, Bronwen E. Shaw, Stefan O. Ciurea, David Gómez Almaguer, Hasan Hashem, Amir Steinberg, Hemant S. Murthy, Raquel M. Schears, Ayami Yoshimi, Linda J. Burns, David Szwajcer, David I. Marks, Tami John, Richard F. Olsson, Charles F. LeMaistre, William A. Wood, Jan Cerny, Susan K. Parsons, David Buchbinder, Usama Gergis, Nosha Farhadfar, Theresa Hahn, Mahmoud Aljurf, Hélène Schoemans, Sherif M. Badawy, Bipin N. Savani, Sara Beattie, Hillard M. Lazarus |
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| Přispěvatelé: | RS: GROW - R3 - Innovative Cancer Diagnostics & Therapy, MUMC+: MA Hematologie (9), Interne Geneeskunde |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Transplantation Conditioning
AYA CHILDHOOD ADOLESCENT outcomes CANCER SURVIVORS immune system diseases hemic and lymphatic diseases Medicine Cumulative incidence Survivors Child intervention OUTCOMES Hematology Incidence (epidemiology) Stem cell transplantation Hematopoietic Stem Cell Transplantation transition health PREVALENCE surgical procedures operative survivor HEALTH Survivor Life Sciences & Biomedicine INTERVENTION TRANSITION Adult medicine.medical_specialty Bone marrow transplantation Immunology prevalence Lost to follow-up stem cell transplantation Article Internal medicine Humans Transplantation Homologous care Aged Transplantation Science & Technology business.industry Proportional hazards model CARE medicine.disease Confidence interval Lymphoma business Follow-Up Studies |
| Zdroj: | Biol Blood Marrow Transplant Biology of Blood and Marrow Transplantation, 26(3), 553-561. Elsevier Science |
| ISSN: | 1083-8791 |
| DOI: | 10.1016/j.bbmt.2019.11.003 |
| Popis: | Follow-up is integral for hematopoietic cell transplantation (HCT) care to ensure surveillance and intervention for complications. We characterized the incidence of and predictors for being lost to follow-up. Two-year survivors of first allogeneic HCT (10,367 adults and 3865 children) or autologous HCT (7291 adults and 467 children) for malignant/nonmalignant disorders between 2002 and 2013 reported to the Center for International Blood and Marrow Transplant Research were selected. The cumulative incidence of being lost to follow-up (defined as having missed 2 consecutive follow-up reporting periods) was calculated. Marginal Cox models (adjusted for center effect) were fit to evaluate predictors. The 10-year cumulative incidence of being lost to follow-up was 13% (95% confidence interval [CI], 12% to 14%) in adult allogeneic HCT survivors, 15% (95% CI, 14% to 16%) in adult autologous HCT survivors, 25% (95% CI, 24% to 27%) in pediatric allogeneic HCT survivors, and 24% (95% CI, 20% to 29%) in pediatric autologous HCT survivors. Factors associated with being lost to follow-up include younger age, nonmalignant disease, public/no insurance (reference: private), residence farther from the tranplantation center, and being unmarried in adult allogeneic HCT survivors; older age and testicular/germ cell tumor (reference: non-Hodgkin lymphoma) in adult autologous HCT survivors; older age, public/no insurance (reference: private), and nonmalignant disease in pediatric allogeneic HCT survivors; and older age in pediatric autologous HCT survivors. Follow-up focusing on minimizing attrition in high-risk groups is needed to ensure surveillance for late effects. ispartof: BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION vol:26 issue:3 pages:553-561 ispartof: location:United States status: published |
| Databáze: | OpenAIRE |
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