Nerve repair by means of vein filled with muscle grafts. II. Morphological analysis of regeneration
| Autor: | Stefano Geuna, Pierluigi Tos, Bruno Battiston, Maria G. Giacobini-Robecchi, Renzo Guglielmone |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Male
medicine.medical_specialty Pathology Time Factors Myelinated nerve fiber medicine.medical_treatment Nerve Fibers Myelinated law.invention law Animals Medicine Peripheral Nerves Rats Wistar business.industry Regeneration (biology) Anatomy Microsurgery Sciatic Nerve Nerve Regeneration Rats Ultrastructure Surgery Histopathology Sciatic nerve Electron microscope business Epineurial repair |
| Zdroj: | Microsurgery. 20:37-41 |
| ISSN: | 1098-2752 0738-1085 |
| DOI: | 10.1002/(sici)1098-2752(2000)20:1<37::aid-micr7>3.0.co;2-5 |
| Popis: | The morphological features of regeneration in long-distance (3 cm) muscle-vein-combined grafts were experimentally investigated in the rat sciatic nerve by means of light and electron microscopy. In the early phases of regeneration (14 days after surgery), many regenerating nerve fibers were detected along the muscle-vein-combined graft. Six months after surgery, quantitative morphometrical analysis of myelinated nerve fibers showed that both the total number and density of myelinated nerve fibers were significantly greater in regenerated nerves than in control nerves. The contrary appeared true for the mean fiber size, with fiber size significantly smaller in regenerated nerves. Ultrastructural observations allowed the description of some peculiar aspects of the relationship between muscle fibers, nerve fibers, and Schwann cells in both early and late phases of regeneration. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text