Left Ventricular Hypertrophic Change Indicating Poor Prognosis in Patients With Normal-Flow, Low-Gradient Severe Aortic Stenosis With Preserved Left Ventricular Ejection Fraction
| Autor: | Nobuyuki Ohte, Yoshihiro Seo, Shohei Kikuchi, Marina Kato, Yu Kawada, Kosuke Nakasuka, Kenta Hachiya, Shuichi Kitada |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Poor prognosis Ejection fraction Preserved left ventricular ejection fraction business.industry medicine.medical_treatment Original article Left ventricular hypertrophy General Medicine Regurgitation (circulation) Normal-flow low-gradient severe aortic stenosis Prognosis medicine.disease Normal flow Stenosis Valvular Heart Disease Internal medicine medicine Cardiology In patient business Watchful waiting |
| Zdroj: | Circulation Reports |
| ISSN: | 2434-0790 |
| DOI: | 10.1253/circrep.cr-21-0011 |
| Popis: | Background: Risk stratification of normal-flow, low-gradient (NFLG) severe aortic stenosis (SAS) with preserved left ventricular (LV) ejection fraction (EF) remains unclear. Methods and Results: Of 289 consecutive patients diagnosed with SAS by aortic valve area 35 mL/m2, mean pressure gradient 115 and >95 mg/m2 for males and females, respectively; HR 3.257; 95% CI 1.172–9.050; P=0.024), and tricuspid regurgitation (TR) velocity (HR 2.761; 95% CI 1.246–6.118; P=0.012). Conclusions: The presence of symptoms, LV hypertrophy, and high TR velocity could be reliable prognostic indicators and may require watchful waiting for timely AVR in patients with NFLG-SAS. |
| Databáze: | OpenAIRE |
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