CHOROIDAL THICKNESS IN CONVALESCENT VOGT–KOYANAGI–HARADA DISEASE
| Autor: | Hiroshi Takase, Manabu Mochizuki, Atsuko Ishizuka, Tatsushi Kawaguchi, Masaru Miyanaga, Hiroyuki Takahashi, Kyoko Ohno-Matsui |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Vogt–Koyanagi–Harada disease medicine.medical_specialty Fundus Oculi Visual Acuity Fundus (eye) immune system diseases hemic and lymphatic diseases Ophthalmology medicine Humans Peripapillary atrophy Stage (cooking) Glucocorticoids Aged Aged 80 and over Choroid business.industry Infant Convalescence General Medicine Middle Aged medicine.disease eye diseases Optic Atrophy surgical procedures operative Pulse Therapy Drug Female sense organs Uveomeningoencephalitic Syndrome business Tomography Optical Coherence |
| Zdroj: | Retina. 34:775-780 |
| ISSN: | 0275-004X |
| DOI: | 10.1097/iae.0b013e3182a6b3f6 |
| Popis: | To evaluate the subfoveal choroidal thickness (SCT) at the convalescent stage of Vogt-Koyanagi-Harada disease and to investigate the correlations among SCT, the presence of the sunset glow fundus, and size of the peripapillary atrophy (PPA).The medical records of consecutive patients with Vogt-Koyanagi-Harada disease without active intraocular inflammation were reviewed, and one eye was randomly chosen for analyses. The disease duration was more than 3 years. Enhanced depth imaging optical coherence tomography was performed to measure SCT. The area of PPA was measured using the PDT/MPS software. Sunset glow fundi were classified into two groups according to the degree of depigmentation.Nineteen eyes with Vogt-Koyanagi-Harada disease were studied. The mean SCT of 12 eyes with severe sunset glow fundus was 144 ± 72 μm which was thinner than that of the 7 eyes with no or mild depigmentation (P = 0.0057). The SCT was inversely correlated with the disease duration (P = 0.048) and the PPA area (P = 0.0002). The PPA area was positively correlated with the disease duration (P = 0.007).The thinner choroid and larger PPA areas were correlated with the degree of depigmentation or disease duration and might be caused by latent choroidal inflammation in the convalescent stage of Vogt-Koyanagi-Harada disease. |
| Databáze: | OpenAIRE |
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