Usefulness of 18F-fluorodeoxyglucose-Positron Emission Tomography in Comparison with Methionine-Positron Emission Tomography in Differentiating Solid Hemangioblastoma from Adult Cerebellar Tumors
| Autor: | Daisuke Yamamoto, Akimasa Nishio, Hajime Kamada, Yoshinobu Takahashi, Naoya Hashimoto |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Pathology medicine.medical_specialty Lymphoma Central nervous system Standardized uptake value 030218 nuclear medicine & medical imaging Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Methionine Fluorodeoxyglucose F18 Hemangioblastoma medicine Humans Cerebellar Neoplasms Aged 80 and over medicine.diagnostic_test business.industry Magnetic resonance imaging Cerebellar Neoplasm Middle Aged medicine.disease medicine.anatomical_structure Positron emission tomography Positron-Emission Tomography Surgery Female Neurology (clinical) Differential diagnosis Radiopharmaceuticals Nuclear medicine business Glioblastoma 030217 neurology & neurosurgery |
| Zdroj: | World neurosurgery. 110 |
| ISSN: | 1878-8769 |
| Popis: | Background and Purpose Among adults with posterior fossa tumors, an intraaxial location of the tumor is less common than an extraaxial location. Moreover, the differential diagnosis of a single cerebellar tumor in adults is sometimes difficult by conventional magnetic resonance imaging. We aimed to report the findings of positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) and methionine in adult patients with intraaxial and solitary metastatic brain tumors. Materials and Methods FDG-PET was performed on 12 patients with posterior fossa tumors: 4 had solid hemangioblastoma (HB), 3 had primary central nervous system lymphomas, 1 had a glioblastoma, and 4 had single metastatic brain tumors (METs). Methionine-PET was performed on 9 patients except for 1 patient with a MET. The maximum standardized uptake value (SUVmax) of the tumor was measured and compared with pathologic findings. Results The SUVmax of FDG in HB was lower compared with that of other tumors (P = 0.001). On the other hand, the SUVmax of methionine in the HB cases was almost the same as that in other tumors (P = 0.07). Conclusion FDG-PET was helpful in differentiating HBs from adult cerebellar tumors. |
| Databáze: | OpenAIRE |
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