The Functional Significance of Endocrine-immune Interactions in Health and Disease
| Autor: | Jamuna Vadivelu, Nagarajan Selvamurugan, Ilangovan Ramachandran, Balasubramanian Vidya, Sridhar Muthusami, Jone A. Stanley, Esaki M. Shankar |
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| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Thyroid Hormones Lactotrophs Dopamine Endocrine System Inflammation Cell Communication Disease Peptide hormone Biology Endocrine System Diseases Bioinformatics Biochemistry Receptors Dopamine 03 medical and health sciences 0302 clinical medicine Immune system medicine Animals Humans Endocrine system Glucocorticoids Molecular Biology Thymocytes Cell Biology General Medicine Somatotrophs Prolactin 030104 developmental biology Immune System Diseases Growth Hormone Immune System Cytokines medicine.symptom 030217 neurology & neurosurgery Endocrine gland Hormone |
| Zdroj: | Current Protein & Peptide Science. 21:52-65 |
| ISSN: | 1389-2037 |
| Popis: | Hormones are known to influence various body systems that include skeletal, cardiac, digestive, excretory, and immune systems. Emerging investigations suggest the key role played by secretions of endocrine glands in immune cell differentiation, proliferation, activation, and memory attributes of the immune system. The link between steroid hormones such as glucocorticoids and inflammation is widely known. However, the role of peptide hormones and amino acid derivatives such as growth and thyroid hormones, prolactin, dopamine, and thymopoietin in regulating the functioning of the immune system remains unclear. Here, we reviewed the findings pertinent to the functional role of hormone-immune interactions in health and disease and proposed perspective directions for translational research in the field. |
| Databáze: | OpenAIRE |
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