Enhancing pathogen identification in patients with meningitis and a negative Gram stain using the BioFire FilmArray® Meningitis/Encephalitis panel
| Autor: | Rodrigo Hasbun, Elizabeth Aguilera, Susan H. Wootton, Lucrecia Salazar, Andrew C. Hemmert |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Adult Male medicine.medical_specialty Adolescent 030106 microbiology Short Report Drug resistance Microbiology law.invention 03 medical and health sciences Young Adult Medical microbiology Aseptic meningitis law medicine Humans In patient Meningitis Child Pathogen Aged Aged 80 and over Bacteria Staining and Labeling business.industry Infant General Medicine Middle Aged medicine.disease Virology Polymerase chain reaction Community-Acquired Infections Gram staining Infectious Diseases Child Preschool Encephalitis Phenazines Female Gentian Violet business Molecular diagnostic techniques |
| Zdroj: | Annals of Clinical Microbiology and Antimicrobials |
| ISSN: | 1476-0711 |
| Popis: | Background Meningitis with a negative cerebrospinal (CSF) Gram stain represents a diagnostic and therapeutic challenge. The purpose of our study was to evaluate the performance of the BioFire FilmArray® Meningitis/Encephalitis (FA ME) panel in patients presenting with community-acquired meningitis with a negative Gram stain. Methods CSF from 48 patients with community-acquired meningitis with a negative Gram stain admitted to four hospitals in Houston, TX underwent additional testing by the FA ME. FA ME results were compared to results obtained as part of routine evaluation. Results The panel detected pathogens not previously identified in 11 (22.9 %) of 48, but did not detect pathogens identified by standard technique (West Nile virus, Histoplasma) in 5 (15.2 %) patients. Conclusions Rapid testing for the most common pathogens causing meningitis will aid in the diagnosis and treatment of patients with meningitis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink