ASO Author Reflections: Impact of the Ratio of the Visceral Fat Area (VFA) to Psoas Muscle Area (PMA) (V/P Ratio) on Survival for Patients with Surgically Resected Esophageal Cancer

Autor: Makoto, Sakai, Makoto, Sohda, Shintaro, Uchida, Arisa, Yamaguchi, Takayoshi, Watanabe, Hideyuki, Saito, Yasunari, Ubukata, Nobuhiro, Nakazawa, Kengo, Kuriyama, Akihiko, Sano, Hiroomi, Ogawa, Takehiko, Yokobori, Ken, Shirabe, Hiroshi, Saeki
Rok vydání: 2022
Předmět:
Zdroj: Annals of Surgical Oncology. 29:4472-4473
ISSN: 1534-4681
1068-9265
Popis: PAST: The true impact of co-occurring muscle mass reduction and fat accumulation on patients with surgically resected esophageal cancer (EC) remains controversial. PRESENT: The current study defined reduction in muscle mass and excess body adiposity as the ratio of the visceral fat area (VFA) to the psoas muscle area (V/P ratio) on the same axial computed tomography slice at the third lumbar vertebra (L3). A high V/P ratio was associated with greater age (p = 0.03), higher body mass index (BMI) (p 0.001), larger VFA (p 0.001), and increased age-adjusted Charlson comorbidity index (ACCI) (p = 0.005). Multivariate analysis showed a high V/P ratio to be an independent prognostic factor for poor overall survival (OS) of EC patients who underwent surgery (p = 0.003). The prognostic value of the V/P ratio still was significant for EC patients with a BMI lower than 25 kg/m
Databáze: OpenAIRE
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