Modern Probe-Assisted Methods for the Specific Detection of Bacteria

Autor: Christophe A. Marquette, Arghavan Shabani, Rosemonde Mandeville, Marcus F. Lawrence
Přispěvatelé: Concordia Univ., Dept Chem & Biochem, Concordia University [Montreal], Génie Enzymatique, Membrane Biomimétique et Assemblages Supramoléculaires (GEMBAS), Institut de Chimie et Biochimie Moléculaires et Supramoléculaires (ICBMS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École Supérieure Chimie Physique Électronique de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-École Supérieure Chimie Physique Électronique de Lyon-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Biophage Pharma, Depierre, Frédérique
Rok vydání: 2015
Předmět:
Zdroj: Journal of Biomedical Science and Engineering (JBISE)
Journal of Biomedical Science and Engineering (JBISE), 2015, 8, pp.104-121
ISSN: 1937-688X
1937-6871
DOI: 10.4236/jbise.2015.82011
Popis: International audience; This review intends to present an overview of methods currently under development for the spe- cific and sensitive detection of pathogenic bacteria that exist in a variety of human environments. Bacteria continue to be a major health threat in general, and much effort is being deployed to counteract this problem. In a first instance, current and efficient techniques in use for the detec- tion of bacteria are described. In a second instance, this review serves to compare the more con- ventional techniques to emerging technologies for the direct (non-labelled) detection of bacteria (referred to as “biosensors”). These approaches are mainly optical, piezoelectric, and electro- chemical in nature. They are cost-effective, quite sensitive, and potentially portable for rapid on- site/real-time detection, and rapid prevention. These devices are comprised of specific chemical/ biochemical probes immobilized onto physical transducers. This work also presents comparisons between the efficiencies (assay time and sensitivity) of various techniques being employed.
Databáze: OpenAIRE