Assessment of Coronary Artery Calcium Scoring to Guide Statin Therapy Allocation According to Risk-Enhancing Factors
| Autor: | Seth S. Martin, Joseph Yeboah, William G. Hundley, Roger S. Blumenthal, Oluseye Ogunmoroti, Khurram Nasir, Salim S. Virani, Michael Y. Tsai, Ramzi Dudum, Jaideep Patel, Nazir Savji, Kiang Liu, Michael D. Miedema, Vincent A. Pallazola, John W. McEvoy, Philip Greenland, Michael J. Blaha, Amy B. Karger, Vasanth Sathiyakumar, Antonio Abbate, Steven Shea, Mary Cushman, Mahmoud Al Rifai |
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| Rok vydání: | 2021 |
| Předmět: |
education.field_of_study
medicine.medical_specialty business.industry Population Guideline medicine.disease Coronary Calcium Score Interquartile range Internal medicine Medicine Metabolic syndrome Family history Cardiology and Cardiovascular Medicine business education Original Investigation Kidney disease Chinese americans |
| Zdroj: | JAMA Cardiol |
| ISSN: | 2380-6583 |
| DOI: | 10.1001/jamacardio.2021.2321 |
| Popis: | IMPORTANCE: The 2018 American Heart Association/American College of Cardiology Guideline on the Management of Blood Cholesterol recommends the use of risk-enhancing factor assessment and the selective use of coronary artery calcium (CAC) scoring to guide the allocation of statin therapy among individuals with an intermediate risk of atherosclerotic cardiovascular disease (ASCVD). OBJECTIVE: To examine the association between risk-enhancing factors and incident ASCVD by CAC burden among those at intermediate risk of ASCVD. DESIGN, SETTING, AND PARTICIPANTS: The Multi-Ethnic Study of Atherosclerosis is a multicenter population-based prospective cross-sectional study conducted in the US. Baseline data for the present study were collected between July 15, 2000, and July 14, 2002, and follow-up for incident ASCVD events was ascertained through August 20, 2015. Participants were aged 45 to 75 years with no clinical ASCVD or diabetes at baseline, were at intermediate risk of ASCVD (≥7.5% to |
| Databáze: | OpenAIRE |
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