Clinical case of combined intestinal infection caused by enteroaggregative Escherichia coli and toxigenic strain Clostridium difficile in a child with cystic fibrosis

Autor: N. V. Gonchar, O. I. Klimova, I. V. Razd'yakonova, A. V. Orlov, A. S. Kvetnaya
Rok vydání: 2021
Předmět:
Zdroj: Žurnal Infektologii, Vol 13, Iss 3, Pp 143-149 (2021)
ISSN: 2072-6732
DOI: 10.22625/2072-6732-2021-13-3-143-149
Popis: The goal is to study the peculiarities of the clinical picture and the distant outcome of intestinal infection due to enteroaggregative escherichiosis and the toxigenic strain of C. difficile in a child with cystic fibrosis.Material and methods. To verify the etiology of intestinal infection, the following studies were conducted. — fecal PCR “OKI-screen” tests to detect viral and bacterial pathogens, fecal bacteriopsy for pathogenic and opportunistic microbes; determination of C. difficile A and B toxins in feces by enzyme-linked fluorescence analysis.Results. The combined intestinal infection caused by en-teroaggregative escherichiosis and a toxigenic strain of C. difficile, in a child with pulmonary-intestinal form of cystic fibrosis was characterized by a wavy course, a pronounced intoxication syndrome, excicosis, hemorrhagic enterocolitis, signs of systemic and local inflammation, metabolic disorders. There were no recurrences of C. difficile-infection in catamnese.Conclusion. It is necessary to continue research on the course of intestinal infections caused by bacterial associations of pathogens.
Databáze: OpenAIRE