Transport carrier tethering - how vesicles are captured by organelles
| Autor: | Sean Munro, Alison K. Gillingham |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
Tethering Vesicle Lipid bilayer fusion Biological Transport Cell Biology Plasma protein binding Biology Membrane Fusion Exocytosis 03 medical and health sciences 0302 clinical medicine Membrane Organelle Biophysics Animals Humans SNARE Proteins Transport Vesicles 030217 neurology & neurosurgery 030304 developmental biology Protein Binding |
| Zdroj: | Current opinion in cell biology. 59 |
| ISSN: | 1879-0410 |
| Popis: | All cells contain numerous membrane-bound organelles that carry out specific functions. These compartments do not, however, act in isolation. Some are in direct contact via membrane contact sites, while others exchange material via specific vesicles or tubular carriers laden with cargo. The term tethering in the context of this review is used to describe the primary recognition and docking of transport carriers with acceptor organelles that occurs before SNARE engagement and membrane fusion. However, it is important to note that other tethering events occur, for example, between organelles in direct contact, which do not lead to fusion. |
| Databáze: | OpenAIRE |
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