Chronic cobalt exposure modifies nociception and orofacial inflammatory pain
| Autor: | VA Grigoras, A. Dondas, Teodora Alexa, Andrei Luca, CR Bohotin, OC Mungiu |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Pathology Neurology business.industry medicine.medical_treatment Pain medicine Clinical Neurology chemistry.chemical_element Ischemic injury General Medicine Cobalt chloride Inflammatory pain Cytokine Endocrinology Nociception Anesthesiology and Pain Medicine chemistry Internal medicine Poster Presentation medicine Neurology (clinical) business Cobalt |
| Zdroj: | The Journal of Headache and Pain |
| ISSN: | 1129-2377 1129-2369 |
| Popis: | Cobalt chloride (CoCl2) is a widely used hypoxia-mimetic; preconditioning with cobalt has been reported to exert protection against ischemic injury as well as decreasing pro-inflammatory cytokine levels ( Shukla et al. 2011 ). Exposure to moderate hypoxia may lead to neurological phenomena such as paraesthesia, numbness or pain, possibly as a consequence of the modifications that appear in small DRG neurones. ( Gruss et al. 2006 ). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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