A novel computerized functional assessment for human immunodeficiency virus-associated neurocognitive disorder

Autor: Heidi Vornbrock Roosa, Amy Eschman, Ned Sacktor, Liana S. Rosenthal, Justin C. McArthur, Richard L. Skolasky, Ola A. Selnes, Richard T. Moxley
Rok vydání: 2013
Předmět:
Adult
Male
medicine.medical_specialty
Neurology
Clinical Neurology
Human immunodeficiency virus (HIV)
HIV Infections
Neuropsychological Tests
medicine.disease_cause
Severity of Illness Index
Article
03 medical and health sciences
Cellular and Molecular Neuroscience
0302 clinical medicine
Virology
Internal medicine
Task Performance and Analysis
Severity of illness
medicine
Humans
Cognitive Dysfunction
In patient
Diagnosis
Computer-Assisted
030212 general & internal medicine
Psychiatry
Depression (differential diagnoses)
Neuropsychological assessment [205]
Depression
HIV [144]
Neuropsychology
Assessment of cognitive disorders/dementia [38]
Hepatitis C
Middle Aged
medicine.disease
3. Good health
Logistic Models
Memory
Short-Term
Female
HIV dementia [34]
Neurology (clinical)
Psychology
Neurocognitive
030217 neurology & neurosurgery
Zdroj: Journal of Neurovirology
ISSN: 1538-2443
1355-0284
Popis: Human immunodeficiency virus (HIV)-associated neurocognitive disorder (HAND) is present in 30–60 % of HIV-positive (HIV+) individuals and can be assessed by neuropsychological testing and level of functional impairment. HAND diagnosis therefore requires accurate assessment of functional impairment. The Computer Assessment of Mild Cognitive Impairment (CAMCI) is a computer-based screening tool that includes performance-based measures of functional impairment. We sought to evaluate the CAMCI as a functional assessment tool in HAND. One hundred fourteen HIV+ patients and 38 HIV-negative (HIV−) patients underwent neuropsychological and CAMCI testing. Cognitive status for HIV+ subjects was classified using the Frascati criteria. HIV+ subjects grouped together and classified by cognitive impairment performed worse than HIV− subjects on several of the CAMCI tasks, including following directions to the supermarket (p = 0.05, p = 0.03), recalling which items to purchase (p = 0.01, p = 0.02), and remembering to stop at a supermarket (p
Databáze: OpenAIRE
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