Antiparasitics in Animal Health: Quo Vadis?
| Autor: | Christian Epe, Paul M. Selzer |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Modalities Antiparasitic Agents Public economics Animal health Parasitic Diseases Animal 030231 tropical medicine Drug Resistance Psychological intervention Isoxazoles Antiparasitic agent 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Infectious Diseases Action (philosophy) Drug Discovery Animals Parasitology Business Market share |
| Zdroj: | Trends in Parasitology. 37:77-89 |
| ISSN: | 1471-4922 |
| DOI: | 10.1016/j.pt.2020.09.004 |
| Popis: | Antiparasitics acting on endo- or ectoparasites represent the second largest segment of the global animal health market, accounting for 23% of market share. However, relatively few novel antiparasitic agents have been introduced into the market during recent decades. One exception, and a groundbreaking 21st century success story, are the isoxazolines, whose full potential has not yet been entirely explored. Unfortunately, resistance issues are present across most parasitic diseases, which generates a clear market need for novel resistance-breaking antiparasitics with new modes/mechanisms of action. Recent advances in science and technologies strongly suggest that the time is right to invest in new modalities such as parasitic vaccines or in environmentally friendly interventions. |
| Databáze: | OpenAIRE |
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