Long-term follow-up after colorectal endoscopic submucosal dissection in 182 cases
| Autor: | Moritz Berger, Tsuneo Oyama, Franz Ludwig Dumoulin, Naohisa Yahagi, Christian Suchy, Ingo Steinbrück |
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| Rok vydání: | 2021 |
| Předmět: |
Original article
medicine.medical_specialty medicine.diagnostic_test Adenoma Long term follow up business.industry Rectum En bloc resection Endoscopic mucosal resection Endoscopic submucosal dissection medicine.disease Endoscopy Surgery Resection 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis medicine lcsh:Diseases of the digestive system. Gastroenterology 030211 gastroenterology & hepatology Pharmacology (medical) lcsh:RC799-869 business |
| Zdroj: | Endoscopy International Open, Vol 09, Iss 02, Pp E258-E262 (2021) Endoscopy International Open |
| ISSN: | 2196-9736 2364-3722 |
| Popis: | Background and study aims We previously reported a case series of our first 182 colorectal endoscopic submucosal dissections (ESDs). In the initial series, 155 ESDs had been technically feasible, with 137 en bloc resections and 97 en bloc resections with free margins (R0). Here, we present long-term follow-up data, with particular emphasis on cases where either en bloc resection was not achieved or en bloc resection resulted in positive margins (R1). Patients and methods Between September 2012 and October 2015, we performed 182 consecutive ESD procedures in 178 patients (median size 41.0 ± 17.4 mm; localization rectum vs. proximal rectum 63 vs. 119). Data on follow-up were obtained from our endoscopy database and from referring physicians. Results Of the initial cohort, 11 patients underwent surgery; follow-up data were available for 141 of the remaining 171 cases (82,5 %) with a median follow-up of 2.43 years (range 0.15–6.53). Recurrent adenoma was observed in 8 patients (n = 2 after margin positive en bloc ESD; n = 6 after fragmented resection). Recurrence rates were lower after en bloc resection, irrespective of involved margins (1.8 vs. 18,2 %; P Conclusions The rate of recurrence is low after en bloc ESD, in particular if a one-piece resection can be achieved. Recurrence after fragmented resection is comparable to published data on piecemeal mucosal resection. |
| Databáze: | OpenAIRE |
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