Salivary bacterial community profile in normal‐weight and obese adolescent patients prior to orthodontic treatment with fixed appliances

Autor: Shima H. Sharara, Leanne M. Cleaver, Hayder Saloom, Guy H. Carpenter, Martyn T. Cobourne
Rok vydání: 2022
Předmět:
Zdroj: Orthodontics & Craniofacial Research. 25:569-575
ISSN: 1601-6343
1601-6335
DOI: 10.1111/ocr.12571
Popis: The aim of this study was to compare the intra-oral bacterial profile of normal-weight and obese adolescents prior to orthodontic treatment with fixed appliances.Nineteen adolescent patients were recruited into two groups based upon body mass index (BMI) and classified as normal-weight or obese. Unstimulated whole mouth saliva was obtained for 5 minutes. Bacterial DNA extraction was performed from saliva, and 16S rRNA gene sequencing of the V1-2 variable regions was undertaken followed by analysis using the mothur pipeline.Saliva from a total of 19 adolescent patients with mean (SD) age 15.6 (1.8) years were divided into 10 normal-weight with mean BMI of 19.4 (2.2) kg/mThere were no differences in alpha or beta diversity of oral bacterial communities between normal-weight and obese orthodontic patients. Obese adolescents attending for orthodontic treatment had a similar microflora to their normal-weight counterparts.
Databáze: OpenAIRE
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