Acidosis and severe megaloblastic anaemia
| Autor: | D Isherwood, Pba Kernoff, IM Franklin, DB Morgan, J Leek |
|---|---|
| Rok vydání: | 1982 |
| Předmět: |
Male
medicine.medical_specialty Anemia Megaloblastic Review Article Gastroenterology Pathology and Forensic Medicine Compensated acidosis hemic and lymphatic diseases Internal medicine medicine Humans Anemia Macrocytic Vitamin B12 Pyruvates Aged Acidosis business.industry Megaloblastic anaemia General Medicine Middle Aged medicine.disease Endocrinology Folic acid Lactic acidosis Lactates Female medicine.symptom business |
| Zdroj: | Journal of Clinical Pathology. 35:984-985 |
| ISSN: | 0021-9746 |
| DOI: | 10.1136/jcp.35.9.984 |
| Popis: | Ten patients with severe megaloblastic anaemia were studied to investigate whether the causative metabolic defects might predispose them to lactic or other acidosis. One patient had compensated acidosis with hyperlactataemia before treatment but there were obvious causes other than anaemia. No other patient developed an acidosis. Neither anaemia per se nor the metabolic defects of vitamin B(12) or folic acid deficiency are likely to cause clinically significant lactic acidosis or hyperlactataemia. |
| Databáze: | OpenAIRE |
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