Hibiscus sabdariffa, a Treatment for Uncontrolled Hypertension. Pilot Comparative Intervention
| Autor: | Fabien Félix, Jaafar Taslimi, Abdulqader Saad Mohammed, Renata Campos Nogueira, Ibrahim Abdullah Khaleel, Marwah Al-Anbaki, Emerson Ferreira Queiroz, Mohammed Najem, Mustafa Shukur Mahmood, Hayder Ali, Laurence Marcourt, Marie Watissée, Anne-Laure Cavin, Hasan Ramadhan Hasan, Bertrand Graz, Jean-Luc Wolfender, Nicolas Vinh Tri Low-Der's |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Hibiscus acid
medicine.medical_specialty hypertension Diastole IDP Decoction Plant Science Intervention group Article 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Hibiscus sabdariffa 030212 general & internal medicine Ecology Evolution Behavior and Systematics Ecology biology business.industry Botany Hibiscus biology.organism_classification refugees Regimen Blood pressure QK1-989 030220 oncology & carcinogenesis Iraq business |
| Zdroj: | Plants Volume 10 Issue 5 Plants, Vol 10, Iss 1018, p 1018 (2021) |
| ISSN: | 2223-7747 |
| Popis: | In Iraq, in 2019, there were about 1.4 million Internally Displaced Persons (IDP) medical treatments were often interrupted. The feasibility of using Hibiscus sabdariffa (HS) decoction to curb hypertension was evaluated. A multicentric comparative pilot intervention for 121 participants with high blood pressure (BP) (≥140/90 mmHg) was conducted. Participants of the intervention group (with or without conventional medication) received HS decoction on a dose regimen starting from 10 grams per day. BP was measured five times over six weeks. The major active substances were chemically quantified. Results: After 6 weeks, 61.8% of participants from the intervention group (n = 76) reached the target BP < 140/90 mmHg, compared to 6.7% in the control group (n = 45). In the intervention group, a mean (±SD) reduction of 23.1 (±11.8) mmHg and 12.0 (±11.2) for systolic and diastolic BP, respectively, was observed, while in the control group the reduction was 4.4 (±10.2)/3.6 (±8.7). The chemical analysis of the starting dose indicated a content of 36 mg of total anthocyanins and 2.13 g of hibiscus acid. The study shows the feasibility of using HS decoction in IDP’s problematic framework, as hibiscus is a safe, local, affordable, and culturally accepted food product. |
| Databáze: | OpenAIRE |
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