Relationship between fatty liver disease and intracranial main artery stenosis
| Autor: | Yuko Ishii, Keisuke Suzuki, Masami Ohrui, Hidehiro Takekawa, Yohei Asakawa, Koichi Hirata |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty Carotid Artery Common Constriction Pathologic Fluid-attenuated inversion recovery Logistic regression Asymptomatic Carotid Intima-Media Thickness Internal medicine medicine.artery Internal Medicine medicine Humans cardiovascular diseases Common carotid artery Aged Aged 80 and over business.industry Cerebral infarction fungi Fatty liver General Medicine Middle Aged medicine.disease Magnetic Resonance Imaging Fatty Liver Stenosis Cerebrovascular Disorders medicine.anatomical_structure Cross-Sectional Studies Case-Control Studies cardiovascular system Cardiology Female medicine.symptom business Artery |
| Zdroj: | Internal medicine (Tokyo, Japan). 53(12) |
| ISSN: | 1349-7235 |
| Popis: | OBJECTIVE The aim of this study was to evaluate the relationship between fatty liver disease (FLD) and cerebrovascular disease. METHODS We conducted a cross-sectional study of 76 consecutive healthy subjects who participated in a two-day hospitalized health checkup program. The maximal intima-media thickness (IMT) of the common carotid artery and bifurcation of the carotid artery as well as the plaque score (PS) were evaluated on carotid artery ultrasonography. Fluid attenuated inversion recovery brain MRI was used to determine the presence of asymptomatic cerebral lesions and periventricular hyperintensity. Brain MR angiography was used to evaluate the degree of intracranial main artery stenosis (ICAS). FLD was diagnosed based on the ultrasonographic pattern. RESULTS The PS and IMT did not differ between the FLD (n=24) and non-FLD (n=52) groups. There was a tendency toward a higher percentage of multiple lacunar lesions in the non-FLD group than in the FLD group. ICAS was significantly more frequent in subjects in the FLD group than those in the non-FLD group (25.0% vs. 5.8%). A logistic regression analysis revealed that age and FLD were significant determinants of ICAS. CONCLUSION Our study findings suggest a significant association between ICAS and FLD. |
| Databáze: | OpenAIRE |
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