A rare case of isoniazid-induced erythroderma
| Autor: | Arun Kumar, Sourabh Jain, Rajeshwari Gore, Yashika Garg |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Drug
medicine.medical_specialty isoniazid Tuberculosis media_common.quotation_subject Antitubercular Agents Histamine Antagonists Erythroderma Severity of Illness Index Drug Watch Adverse cutaneous drug reaction Rare case Severity of illness medicine Humans Pharmacology (medical) Tuberculosis Pulmonary media_common Pharmacology business.industry Pruritus erythroderma Isoniazid Middle Aged medicine.disease Dermatology Combined Modality Therapy Surgery Directly Observed Therapy Treatment Outcome Itching Drug Therapy Combination Female Drug Eruptions medicine.symptom business Adverse drug reaction Dermatitis Exfoliative medicine.drug |
| Zdroj: | Indian Journal of Pharmacology |
| ISSN: | 1998-3751 |
| Popis: | Tuberculosis is a common infectious disease in developing countries. Isoniazid is established the first-line antitubercular drug and an essential component of all antitubercular regimens. Erythroderma caused by isoniazid is an uncommon but serious adverse drug reaction. We report here a case of a 63-year-old female patient who presented with generalized redness and scaling with itching after 8 weeks of antitubercular treatment (ATT). ATT was stopped immediately, and antihistaminics were started. The patient improved over a period of 2 weeks. On sequential rechallenge, she developed similar lesions all over the body with isoniazid, hence confirming the diagnosis of isoniazid-induced erythroderma. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|