Clinical trial with testosterone undecanoate for male fertility control
| Autor: | H. Hoogen, H. Schuster, Eberhard Nieschlag, E.J. Wickings, M. Bölk |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Adult
Male medicine.medical_specialty Administration Oral Follicle-stimulating hormone Internal medicine medicine Endocrine system Ingestion Humans Testosterone Spermatogenesis business.industry Obstetrics and Gynecology Oligospermia Spermatozoa Prolactin Spermatogenesis-Blocking Agents Endocrinology Fertility Reproductive Medicine Depression Chemical Sperm Motility Luteinizing hormone business Hormone |
| Zdroj: | Contraception. 18(6) |
| ISSN: | 0010-7824 |
| Popis: | The newly available orally effective testosterone undecanoate (TU) was investigated as a possible means for male fertility control. One of 7 normal volunteers exposed to 80 mg TU three times a day for 10–12 weeks became azoospermic, the remaining showed slightly suppressed or unaffected sperm counts. The insufficient suppression of spermatogenesis in 6 out of 7 subjects may be due to the fact that testosterone levels are only sufficiently high to suppress gonadotropins for some hours after ingestion of the drug. |
| Databáze: | OpenAIRE |
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