Dithiol‐Activated Bioorthogonal Chemistry for Endoplasmic Reticulum‐Targeted Synergistic Chemophototherapy

Autor: Jian Sun, Xiaoran Zhang, Xia Wang, Jinlei Peng, Gang Song, Yufei Di, Fude Feng, Shu Wang
Rok vydání: 2022
Předmět:
Zdroj: Angewandte Chemie. 134
ISSN: 1521-3757
0044-8249
DOI: 10.1002/ange.202213765
Popis: The controlled intracellular release of nitrite is still an unmet challenge due to the lack of bio-friendly donors, and the antitumor effect of nitrite is limited by its physiologically inert activity. Herein, we designed benzothiadiazole-based organic nitrite donors that are stable against bio-relevant species but selectively respond to dithiol species through S
Databáze: OpenAIRE
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