Hysteroscopic Assessment of Menopausal Breast-Cancer Patients Taking Tamoxifen; There is a Bias from the Mode of Endometrial Sampling in Estimating Endometrial Morbidity?
| Autor: | Francesco Grossi, Fulvia Cellani, Massimo Luerti, Giovanna Centinaio, Giancarlo Garuti, Monica Colonnelli |
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| Rok vydání: | 2002 |
| Předmět: |
Cancer Research
medicine.medical_specialty Antineoplastic Agents Hormonal medicine.medical_treatment Breast Neoplasms Hysteroscopy Endometrium Sensitivity and Specificity Breast cancer medicine Endometrial Polyp Humans Ultrasonography Gynecology medicine.diagnostic_test business.industry Endometrial cancer Middle Aged medicine.disease Curettage Endometrial Neoplasms Menopause Tamoxifen medicine.anatomical_structure Oncology Female business medicine.drug |
| Zdroj: | Breast Cancer Research and Treatment. 72:245-253 |
| ISSN: | 1573-7217 0167-6806 |
| Popis: | The aim of this study is to evaluate the accuracy of hysteroscopy in detecting tamoxifen-associated endometrial morbidity. Ninety-eight menopausal breast cancer patients taking tamoxifen underwent hysteroscopy because of an endometrial thickness above 4 mm measured by Transvaginal Ultrasonography. Thirty-one women recorded uterine bleeding while 67 were asymptomatic. Hysteroscopies with operative facilities were performed, mainly in out-patient setting. Hysteroscopic findings were matched with histopathology derived from various modalities of tissue collection as suction-curettage, oriented-streak curettage, hysteroscopically-targeted biopsies or polypectomies and hysterectomies. Accuracy of hysteroscopy to estimate a normal or abnormal endometrium was calculated. Abnormal endometrium was detected in 35 patients (64.5% in symptomatic and 22.3% in asymptomatic women, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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