A critical evaluation of bioimpedance spectroscopy analysis in estimating body composition during GH treatment: comparison with bromide dilution and dual X-ray absorptiometry
| Autor: | Chong-Hui Khaw, Anne E. Nelson, Udo J. Meinhardt, Vita Birzniece, Ken K. Y. Ho |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Bromides Male medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism Composition analysis Fat mass Young Adult chemistry.chemical_compound Absorptiometry Photon Endocrinology Animal science Double-Blind Method Bioimpedance spectroscopy Bromide Internal medicine medicine Humans Dual x-ray absorptiometry Human Growth Hormone General Medicine Dilution Treatment Outcome chemistry Dielectric Spectroscopy Body Composition Gh treatment Female Composition (visual arts) human activities |
| Zdroj: | European Journal of Endocrinology. 172:21-28 |
| ISSN: | 1479-683X 0804-4643 |
| Popis: | ObjectiveTo compare estimates by bioimpedance spectroscopy analysis (BIS) of extracellular water (ECW), fat mass (FM), and fat-free mass (FFM) against standard techniques of bromide dilution and dual energy X-ray absorptiometry (DXA) during intervention that causes significant changes in water compartments and body composition.MethodsBody composition analysis using BIS, bromide dilution, and DXA was performed in 71 healthy recreational athletes (43 men, 28 women; aged 18–40 years; BMI 24±0.4 kg/m2) who participated in a double-blinded, randomized, placebo-controlled study of GH and testosterone treatment. The comparison of BIS with bromide dilution and DXA was analyzed using linear regression and the Bland–Altman method.ResultsAt baseline, there was a significant correlation between BIS and bromide dilution-derived estimates for ECW, and DXA for FM and FFM (PPPConclusionIn healthy adults, bioimpedance spectroscopy is an acceptable tool for measuring ECW; however, BIS overestimates FFM and substantially underestimates FM compared with DXA. |
| Databáze: | OpenAIRE |
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