The impact of a multifaceted intervention including sepsis electronic alert system and sepsis response team on the outcomes of patients with sepsis and septic shock

Autor: Ra’ed Hijazi, Abdulaziz Al-Dawood, Amal Matroud, Yaseen M. Arabi, Hasan M. Al-Dorzi, Shihab Mundekkadan, Sami Alsolamy, Saadi Taher, Hani Tamim, Abdellatif M. Marini, Fatimah H. Al Ehnidi, Mohamed Salih Aziz Mohamed, Saad Al-Qahtani, Ahmed Alamry, Majid Al Salamah
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Annals of Intensive Care, Vol 7, Iss 1, Pp 1-10 (2017)
Annals of Intensive Care
BASE-Bielefeld Academic Search Engine
ISSN: 2110-5820
DOI: 10.1186/s13613-017-0280-7
Popis: Background Compliance with the clinical practice guidelines of sepsis management has been low. The objective of our study was to describe the results of implementing a multifaceted intervention including an electronic alert (e-alert) with a sepsis response team (SRT) on the outcome of patients with sepsis and septic shock presenting to the emergency department. Methods This was a pre–post two-phased implementation study that consisted of a pre-intervention phase (January 01, 2011–September 24, 2012), intervention phase I (multifaceted intervention including e-alert, from September 25, 2012–March 03, 2013) and intervention phase II when SRT was added (March 04, 2013–October 30, 2013) in a 900-bed tertiary-care academic hospital. We recorded baseline characteristics and processes of care in adult patients presenting with sepsis or septic shock. The primary outcome measures were hospital mortality. Secondary outcomes were the need for mechanical ventilation and length of stay in the intensive unit and in the hospital. Results After implementing the multifaceted intervention including e-alert and SRT, cases were identified with less severe clinical and laboratory abnormalities and the processes of care improved. When adjusted to propensity score, the interventions were associated with reduction in hospital mortality [for intervention phase II compared to pre-intervention: adjusted odds ratio (aOR) 0.71, 95% CI 0.58–0.85, p = 0.003], reduction in the need for mechanical ventilation (aOR 0.45, 95% CI 0.37–0.55, p
Databáze: OpenAIRE