Prothrombin in newborns and during the first year of life
| Autor: | I. Noren, E. Carlsson, G. Kretzschmar, A.-C. Teger-Nilsson |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Vitamin K Pregnancy in Diabetics First year of life Gestational Age Vitamin k Hematocrit Gastroenterology Plasma Pre-Eclampsia Pregnancy hemic and lymphatic diseases Internal medicine Methods Medicine Humans Hypoprothrombinemias Normal range Prothrombin time medicine.diagnostic_test business.industry Infant Newborn Gestational age Infant General Medicine medicine.disease Pediatrics Perinatology and Child Health Prothrombin Time Female Prothrombin business Adult level circulatory and respiratory physiology |
| Zdroj: | Acta paediatrica Scandinavica. 60(3) |
| ISSN: | 0001-656X |
| Popis: | Summary Prothrombin concentration, determined specifically with a new two-stage method, was compared with thrombotest activity in samples from infants, aged 0–21 days. There was a significant correlation between the two methods. Effect of treatment with vitamin K and plasma was registered with both methods. As the distribution of prothrombin and thrombotest values from normal, full-term neonates was slightly skew, mean value and S.D. was calculated from the logarithmic values. The normal range, expressed as mean ± 2 S.D. was for prothrombin 26–85 % and for thrombotest 27–74% (values corrected for hematocrit). No bleeding was observed in any patient with prothrombin above 20% and thrombotest above 22% (corrected values). Most low values in newborns were found in children suffering from hypoxia. Prothrombin concentration was also compared with prothrombin-proconvertin activity in samples from children, aged 0–12 months. In the healthy child prothrombin values reached the normal adult level at the age of 6–12 months, prothrombin-proconvertin values at the age of about 3 months. |
| Databáze: | OpenAIRE |
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