Popis: |
Background and Objectives: Lignocaine Hydrochloride (HCl), an amide group of local anaesthetic continues to be used as the preferred local anaesthetic agent in exodontia. Alternatives such as diphenhydramine, an antihistamine is used in cases of allergy exhibited towards amide or ester group of local anaesthetic agents. Other alternatives such as opioids like tramadol hydrochloride (HCl) have recently shown peripheral anaesthetic activity. The present double-blinded splitmouth clinical study aimed to evaluate and compare the clinical anaesthetic efficacy, analgesic effect, and limitations of lignocaine HCl and tramadol HCl in orthodontic extractions. Methods: 100 cases were selected for the orthodontic extraction of maxillary premolars. 50 healthy and ambulatory individuals of both sexes, aged 18- 30 years undergoing extraction of bilateral maxillary premolar teeth for orthodontic treatment, fulfilling the inclusion criteria were selected for the study. |