Experimental assessment of spectrum analysis of ultrasonic echoes as a method for estimating scatterer properties
| Autor: | Tetsuya Hosokawa, Jeffrey R. Justin, George P. Tuszynski, J Machi, Bernard Sigel, R. V. Kolecki, Teruo Kakegawa, Hiroshi Kitamura, Ernest J. Feleppa |
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| Rok vydání: | 1994 |
| Předmět: |
Longest Diameter
Lung Neoplasms Materials science Acoustics and Ultrasonics Radiological and Ultrasound Technology business.industry Attenuation Biophysics Spectral density Ranging Function (mathematics) Transducer Optics Tumor Cells Cultured Humans Ultrasonics Radiology Nuclear Medicine and imaging Ultrasonic sensor Scattering theory business Ultrasonography |
| Zdroj: | Ultrasound in Medicine & Biology. 20:463-470 |
| ISSN: | 0301-5629 |
| DOI: | 10.1016/0301-5629(94)90101-5 |
| Popis: | In vitro experiments using weak scatterers ranging in size from mean longest diameter of 26.9 to 83.0 microns were performed to test the validity of theoretical predictions for scatterer size and concentration derived from normalized power spectrum parameters of ultrasonic backscatterer echoes. Scatterers consisting of cell clusters were suspended in collagen gel and scanned by a 10 MHz transducer system. Optical measurements validated theoretical predictions that (1) slope value is a function solely of scatterer size; (2) intercept value is a function of scatterer size and concentration; and (3) midband fit value increases as scatterer concentration increases, and, to a lesser extent, as size increases. These results were obtained under relatively ideal conditions of minimal attenuation and scatterer spacing (not closer than two scatterer diameters) and were consistent with the assumptions underlying the scattering theory. |
| Databáze: | OpenAIRE |
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