Maggot therapy for chronic ulcer: A retrospective cohort and a meta-analysis
| Autor: | Suwannee Eamkong, Chumpon Wilasrusmee, Ammarin Thakkinstian, Napaphat Poprom, Sopon Jirasisrithum, Mongkol Marjareonrungrung, John Attia |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Chronic wound
Male medicine.medical_specialty wound therapy lcsh:Surgery Cohort Studies Maggot therapy Medicine Animals Humans music chronic wound Retrospective Studies music.instrument business.industry Diptera Hazard ratio Surgical wound Retrospective cohort study lcsh:RD1-811 Middle Aged maggot wound therapy medicine.disease Diabetic foot Diabetic Foot Surgery Diabetic foot ulcer Larva Female chronic ulcer medicine.symptom business maggot human activities Cohort study |
| Zdroj: | Scipedia Open Access Scipedia SL Asian Journal of Surgery, Vol 37, Iss 3, Pp 138-147 (2014) |
| Popis: | Background/Objective: Maggot wound therapy (MWT) has been used in various wounds including diabetic foot ulcers, venous leg ulcers, pressure ulcers, and acute surgical wounds. However, the efficacy of MWT therapy has been controversial. We therefore conducted a cohort study and a meta-analysis to assess MWT effects. Methods: A retrospective cohort study was performed in diabetic foot ulcer (DFU) patients who were treated with MWT or conventional wound therapy (CWT) in Thailand. The Kaplan-Meier curve was applied to estimate the healing probability. A meta-analysis was performed to pool our study with four previous cohort studies identified from Medline and Scopus. Results: The estimated incidence of wound healing was 5.7/100 (95% CI: 4.49, 7.32) patients-week, and the median time to healing was 14 weeks. The hazard ratio (HR) of wound healing was 7.87 times significantly higher in the MWT than the CWT (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|