Association of Iron Status and Intake During Pregnancy with Neuropsychological Outcomes in Children Aged 7 Years: The Prospective Birth Cohort Infancia y Medio Ambiente (INMA) Study

Autor: Sabrina Llop, Izaro Babarro, Jesús Ibarluzea, Jordi Julvez, Jordi Sunyer, Mònica Tous, Raquel Soler-Blasco, Sílvia Fernández-Barrés, Carmen Hernández-Martínez, Mònica Guxens, Victoria Arija, Josefa Canals, Jesús Vioque
Přispěvatelé: Child and Adolescent Psychiatry / Psychology
Rok vydání: 2019
Předmět:
Male
0301 basic medicine
Pediatrics
attention
executive function
iron intake
iron status
neuropsychological function
pregnancy
working memory
Trail Making Test
iron intake
Neuropsychological Tests
neuropsychological function
Executive Function
Child Development
Cognition
0302 clinical medicine
Pregnancy
Attention
Prospective Studies
030212 general & internal medicine
iron status
Child
education.field_of_study
Nutrition and Dietetics
Neuropsychology
Iron deficiency
3. Good health
Memory
Short-Term
Cohort
Female
pregnancy
Iron
Dietary
Adult
medicine.medical_specialty
Offspring
Iron
Population
Nutritional Status
Article
working memory
03 medical and health sciences
medicine
Humans
Cognitive skill
education
030109 nutrition & dietetics
business.industry
Maternal Nutritional Physiological Phenomena
medicine.disease
attention
executive function
Spain
business
Food Science
Zdroj: Nutrients
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname
Nutrients, 11(12):2999. Multidisciplinary Digital Publishing Institute (MDPI)
Volume 11
Issue 12
r-FISABIO. Repositorio Institucional de Producción Científica
ISSN: 2072-6643
Popis: Early iron status plays an important role in prenatal neurodevelopment. Iron deficiency and high iron status have been related to alterations in child cognitive development
however, there are no data about iron intake during pregnancy with other environmental factors in relation to long term cognitive functioning of children. The aim of this study is to assess the relationship between maternal iron status and iron intake during pregnancy and child neuropsychological outcomes at 7 years of age. We used data from the INMA Cohort population-based study. Iron status during pregnancy was assessed according to serum ferritin levels, and iron intake was assessed with food frequency questionnaires. Working memory, attention, and executive function were assessed in children at 7 years old with the N-Back task, Attention Network Task, and the Trail Making Test, respectively. The results show that, after controlling for potential confounders, normal maternal serum ferritin levels (from 12 mg/L to 60 mg/L) and iron intake (from 14.5 mg/day to 30.0 mg/day), respectively, were related to better scores in working memory and executive functioning in offspring. Since these functions have been associated with better academic performance and adaptation to the environment, maintaining a good state of maternal iron from the beginning of pregnancy could be a valuable strategy for the community.
Databáze: OpenAIRE
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