Relationship between the FRAX index and physical and cognitive functioning in older people
| Autor: | Jésica Abadía Otero, Yolanda González Silva, J. L. Pérez-Castrillón, Teresa Murcia Casado, Laura Abad Manteca, MaríaLuisa Rodríguez Carbajo, Mónica Álvarez Muñoz, Lourdes Ausín Pérez, Henar de la Red Gallego |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
FRAX Index (economics) 030209 endocrinology & metabolism Neuropsychological Tests Logistic regression Risk Assessment 03 medical and health sciences 0302 clinical medicine Cognition Bone Density Risk Factors medicine Humans Cognitive Dysfunction 030212 general & internal medicine Geriatric Assessment Aged Aged 80 and over Hip fracture Mini–Mental State Examination medicine.diagnostic_test business.industry Hip Fractures Area under the curve Age Factors General Medicine medicine.disease Comorbidity Osteoporosis Observational study Female business Osteoporotic Fractures Demography |
| Zdroj: | Annals of medicine. 50(6) |
| ISSN: | 1365-2060 |
| Popis: | To assess the relationship between the FRAX index and the Barthel index/MiniMental State Examination in older people.Observational descriptive study. Demographic data, comorbidity, dependency and cognitive state, and risk of osteoporotic fracture were collected.A total of 375 patients were included (60% female) Patients with a low-risk FRAX for hip fractures had a higher Mini-mental (25, 95% CI = 24-27 vs. 22, 95% = 21 to 23, p = .0001), a higher Barthel index (88, 95% CI = 84-93 vs 72, 69 to 76, p = .0001) without differences in the Charlson index. Bivariate analysis showed an inverse association between FRAX and scales but logistic regression showed only female sex (OR 4.4, 95% CI = 2.6-7.6) and the non-dependent Barthel index (OR = 0.104, 95% CI = 0.014-0.792) remained significant and. Barthel index/Mini-mental constructed a significant model capable of predicting a risk of hip fracture of3% measured by the FRAX index, with an area under the curve of 0.76 (95% CI = 0.7-0.81).The FRAX index is related to other markers of geriatric assessment and the association between these variables can predict a risk of hip fracture of3% measured by the FRAX index. Key messages Geriatric assessment indexes may be as important as the FRAX index, which is based on clinical risk factors, in predicting the fracture risk in older patient. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|