Pattern of Presentation and Surgical Management of Spine Tumors in Southeast Nigeria over a 10‑Year Period
| Autor: | Wilfred C Mezue, Sunday Nkwerem, Linda U. Iroegbu, Okwuoma Okwunodulu, M Messi, Samuel C Ohaegbulam, Mark C Chikani, Chika Anele Ndubuisi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Thoracic spine Nigeria Adenocarcinoma Neurosurgical Procedures Spinal Cord Diseases Young Adult Thoracic region medicine Humans Spinal Cord Neoplasms Neoplasm Metastasis Retrospective Studies Spinal Neoplasms medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Odds ratio Middle Aged Spinal cord Magnetic Resonance Imaging Spine Spine (zoology) Treatment Outcome medicine.anatomical_structure Radiological weapon Cervical Vertebrae Female Radiology Presentation (obstetrics) business Metastatic spinal cord spine tumors surgery |
| Zdroj: | Nigerian Journal of Clinical Practice; Vol. 23 No. 8 (2020); 1167-1171 |
| ISSN: | 1119-3077 |
| Popis: | Background:Spine tumors could affect the bony elements and/or its neural contents. Clinical manifestations are underlined by their biological behaviors. Aim: This study aims to identify the pattern of presentation and surgical management of spine tumors in southeast Nigeria over a 10-year period.Patients and Methods:A retrospective analysis of patients who were managed surgically for the spine and spinal cord neoplastic lesions over a 10-year period. All patients had pre-and post-operative magnetic resonance imaging (MRI) and histological diagnosis. Relevant clinical, radiological, and histological data were extracted and analyzed using Statistical Package for the Social Sciences (SPSS) for windows version 21.Results:Four hundred and seventy-two spine procedures performed within the study period, 39 cases of histologically proven primary spinal cord tumors (PSCT) and non-PSCT were identified. These represented 8.3% of spine procedures. Seventeen were PSCT (3.6% of spine procedures), while 22 (4.7%) had non-PSCT, mean age for the PSCT group was 45 yrs and non-PSCT 59.5 years. A total of 56.5% of tumors are involved in the thoracic region, 43.7% in the cervical region. PSCT was likely to affect the cervical spine; while bony spine tumors, thoracic spine [odds ratio (OR) 4.9,Pvalue 0.019]. A total of 84.6% of non-PSCT affected the bony spine, mainly the vertebral body. The histological result showed metastatic adenocarcinoma to be the most common tumor (33.3%). PSCT was likely to be benign than non-PSCT (P value < 0.00001). Gross total resection (GTR) was done in 100% of PSCT, and 50% in non-PSCT. Thirteen (40.6%) patients improved and 11 (34.4%) patients remained the same. Conclusions:Metastatic adenocarcinoma was the most common tumor of the spine. There was restricted ability at a GTR for non-PSCT compared to PSCT. Grossly 75% had improved/same neurological status, as such adjudged as a good outcome. |
| Databáze: | OpenAIRE |
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