Dose Response on the Faecal Colonisation of Lactobacillus Strain GG Administered in Two Different Formulations
| Autor: | Seppo Salminen, M. Saxelin, M. Ahokas |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: |
0303 health sciences
Lactobacillus GG biology 030306 microbiology Lactobacillus strain General Engineering food and beverages Lactobacillaceae biology.organism_classification 3. Good health law.invention Colonisation 03 medical and health sciences Probiotic Oral administration law Lactobacillus General Earth and Planetary Sciences Food science Feces 030304 developmental biology General Environmental Science |
| Zdroj: | Microbial Ecology in Health and Disease; Vol 6, No 3 (1993) |
| ISSN: | 1651-2235 |
| Popis: | Faecal concentrations of Lactobacillus GG in human subjects were studied after oral administration of the bacterium Lactobacillus GG was given in total to 44 healthy human volunteers for 7 d as enterocoated tablets with daily doses of 1 x 10 9 c.f.u., 4 x l0 9 and 8 x l0 9 c.f.u. and in fermented milk with daily doses of 2 · 1 x 10 9 c.f.u. and 1 · 2 x 10 10 c.f.u. All the volunteers excreted the organism by day 3 of the test period. There were no statistical differences in mean faecal Lactobacillus GG contents between the tablet groups. With fermented milk there was a clear, statistically significant increase in mean faecal Lactobacillus GG content when the administration was 1 · 2 x 10 10 c.f.u./d compared to 2 · 1 x l0 9 c.f.u./d. The results indicate that fermented milk and enterocoated tablets are good carriers for administering Lactobacillus GG as a probiotic organism. Keywords - Lactobacillus GG; Faecal colonisation; Human probiotic. |
| Databáze: | OpenAIRE |
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