High-intensity interval training is effective and superior to moderate continuous training in patients with heart failure with preserved ejection fraction: A randomized clinical trial
| Autor: | Maurice Zanini, Débora dos Santos Macedo, Juliana Beust de Lima, Diogo da Silva Piardi, Ricardo Stein, Jari A. Laukkanen, Rosane Maria Nery, Anderson Donelli da Silveira |
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| Rok vydání: | 2020 |
| Předmět: |
Male
medicine.medical_specialty Epidemiology Diastole Exercise intolerance 030204 cardiovascular system & hematology High-Intensity Interval Training Ventricular Function Left law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law Internal medicine medicine Humans Single-Blind Method 030212 general & internal medicine Retrospective Studies Heart Failure Ejection fraction Exercise Tolerance business.industry Stroke Volume Middle Aged medicine.disease Continuous training Exercise Therapy Treatment Outcome Echocardiography Heart failure Cardiology Exercise Test Quality of Life Female medicine.symptom Cardiology and Cardiovascular Medicine business Heart failure with preserved ejection fraction High-intensity interval training |
| Zdroj: | European journal of preventive cardiology. 27(16) |
| ISSN: | 2047-4881 |
| Popis: | Background Heart failure with preserved ejection fraction (HFpEF) is a prevalent syndrome, with exercise intolerance being one of its hallmarks, contributing to worse quality of life and mortality. High-intensity interval training is an emerging training option, but its efficacy in HFpEF patients is still unknown. Design Single-blinded randomized clinical trial. Methods Single-blinded randomized clinical trial with exercise training 3 days per week for 12 weeks. HFpEF patients were randomly assigned to high-intensity interval training or moderate continuous training. At baseline and after 12 week follow-up, patients underwent clinical assessment, echocardiography and cardiopulmonary exercise testing (CPET). Results Mean age was 60 ± 9 years and 63% were women. Both groups ( N = 19) showed improved peak oxygen consumption (VO2), but high-intensity interval training patients ( n = 10) had a significantly higher increase, of 22%, compared with 11% in the moderate continuous training ( n = 9) individuals (3.5 (3.1 to 4.0) vs. 1.9 (1.2 to 2.5) mL·kg−1·min−1, p Conclusions This randomized clinical trial provided evidence that high-intensity interval training is a potential exercise modality for HFpEF patients, being more effective than moderate continuous training in improving peak VO2. However, the two strategies were equally effective in improving ventilatory efficiency and other CPET parameters, quality of life score and diastolic function after 3 months of training. |
| Databáze: | OpenAIRE |
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