Highly Efficient F, Cu doped TiO2 anti-bacterial visible light active photocatalytic coatings to combat hospital-acquired infections
| Autor: | Nigel S. Leyland, Suresh C. Pillai, John A. Browne, Steven J. Hinder, Brid Quilty, Joanna Podporska-Carroll |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Light Surface Properties Photocatalytic coatings Highly efficient F Cu doped TiO2 02 engineering and technology Microbial Sensitivity Tests Bacterial growth 010402 general chemistry medicine.disease_cause 01 natural sciences Article Catalysis chemistry.chemical_compound Fluorides Coated Materials Biocompatible X-Ray Diffraction Superhydrophilicity Nosocomial infections Medicine and Health Sciences medicine Humans Life Sciences ITS Titanium anti-bacterial visible light active photocatalytic coatings Hospital-acquired infections Cross Infection Multidisciplinary Bacteria Chemistry Photoelectron Spectroscopy Highly Efficient F 021001 nanoscience & nanotechnology Cu doped TiO2 Methicillin-resistant Staphylococcus aureus 0104 chemical sciences Surgery Anti-Bacterial Agents Staphylococcus aureus Titanium dioxide Photocatalysis 0210 nano-technology Antibacterial activity Copper Visible spectrum Nuclear chemistry |
| Zdroj: | Scientific Reports Articles |
| ISSN: | 2045-2322 |
| Popis: | Bacterial infections are a major threat to the health of patients in healthcare facilities including hospitals. One of the major causes of patient morbidity is infection with Staphylococcus aureus. One of the the most dominant nosocomial bacteria, Methicillin Resistant Staphylococcus aureus (MRSA) have been reported to survive on hospital surfaces (e.g. privacy window glasses) for up to 5 months. None of the current anti-bacterial technology is efficient in eliminating Staphylococcus aureus. A novel transparent, immobilised and superhydrophilic coating of titanium dioxide, co-doped with fluorine and copper has been prepared on float glass substrates. Antibacterial activity has demonstrated (by using Staphylococcus aureus), resulting from a combination of visible light activated (VLA) photocatalysis and copper ion toxicity. Co-doping with copper and fluorine has been shown to improve the performance of the coating, relative to a purely fluorine-doped VLA photocatalyst. Reductions in bacterial population of log10 = 4.2 under visible light irradiation and log10 = 1.8 in darkness have been achieved, compared with log10 = 1.8 under visible light irradiation and no activity, for a purely fluorine-doped titania. Generation of reactive oxygen species from the photocatalytic coatings is the major factor that significantly reduces the bacterial growth on the glass surfaces. |
| Databáze: | OpenAIRE |
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