Clinical signs for identification of neurocysticercosis in swine naturally infected with Taenia solium
| Autor: | Nuzhat Husain, Amit Prasad, Mukesh Tripathi, Kashi N. Prasad, Sanjeev Chawla, Rakesh K. Gupta |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Pathology medicine.medical_specialty Swine Neurocysticercosis Zoonotic disease Diagnosis Differential Taenia solium parasitic diseases medicine Animals Excessive Blinking Saliva Swine Diseases medicine.diagnostic_test urogenital system business.industry Brain Magnetic resonance imaging Magnetic Resonance Imaging Disease Models Animal Taenia solium infection medicine.drug_formulation_ingredient Infectious Diseases Tears embryonic structures Female Parasitology Histopathology Cysticercus cellulosae business |
| Zdroj: | Parasitology International. 55:151-154 |
| ISSN: | 1383-5769 |
| DOI: | 10.1016/j.parint.2006.01.002 |
| Popis: | Taenia solium infection is a zoonotic disease and swine is the natural intermediate host. Till date no literatures have described clinical signs in swine indicative of brain involvement by cysticerci. In the present study we describe such clinical signs of porcine neurocysticercosis (NCC). These signs were excessive salivation, excessive blinking and tearing, and subconjunctival nodule. A total of 30 swine (18 with 2 or all 3 clinical signs and 12 without any sign) underwent magnetic resonance imaging (MRI). All 18 swine with above signs had NCC on MRI along with variable involvement of other organs that were subsequently confirmed by ex vivo MRI, necropsy and histopathology, while none of the 12 animals without any sign had NCC. As development of a porcine NCC model has proved difficult, we propose that naturally infected swine can be identified on the basis of these clinical signs and thus used as a model for further research on NCC. |
| Databáze: | OpenAIRE |
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