Correlation of lactic acid level, cell count and cytology in cerebrospinal fluid of patients with bacterial and non-bacterial meningitis
| Autor: | H W. Kölmel, M von Maravic |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
Pathology
medicine.medical_specialty Cell Andrology chemistry.chemical_compound Cerebrospinal fluid CSF pleocytosis Cytology Leukocytes medicine Humans Meningitis Lactic Acid business.industry Cerebral hypoxia Bacterial Infections General Medicine medicine.disease Lactic acid medicine.anatomical_structure Neurology chemistry Lactates Encephalitis Neurology (clinical) business |
| Zdroj: | Acta Neurologica Scandinavica. 78:6-9 |
| ISSN: | 1600-0404 0001-6314 |
| DOI: | 10.1111/j.1600-0404.1988.tb03610.x |
| Popis: | The relation between lactate concentration and cell count was determined in 394 CSF samples from unselected patients. In addition, a similar analysis was performed in 156 CSF samples from patients with bacterial and non-bacterial meningitis. The correlation between cell type and lactate level was also examined. The analysis demonstrated a significant linear increase in lactate showing high lactate levels at cell counts above 350 cells per microliter. Since the lactic acid concentration in bacterial meningitis increases linearly with the number of lactate-producing cells, it may be concluded that the increased lactate concentration results from CSF pleocytosis. If lactate levels are higher than the normal distribution, additional sources of lactate production such as cerebral hypoxia must be assumed. |
| Databáze: | OpenAIRE |
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