Differences in hemodynamic characteristics under high packing density between the porous media model and finite element analysis in computational fluid dynamics of intracranial aneurysm virtual treatment
| Autor: | Sufang Zhang, Lei Huang, Xiaolong Zhang, Gaohui Li, Hailin Wan, Liang Ge, Xiaochang Leng, Ruoyu Di, Jianping Xiang, Gang Lu, Yeqing Jiang, Daoying Geng |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Finite Element Analysis Hemodynamics Computational fluid dynamics 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Nuclear magnetic resonance Aneurysm medicine Humans Aged business.industry Models Cardiovascular Virtual Reality Intracranial Aneurysm General Medicine Blood flow Middle Aged Flow pattern medicine.disease Finite element method Sphere packing Hydrodynamics Female Surgery Stress Mechanical Neurology (clinical) business Porosity Parent vessel 030217 neurology & neurosurgery |
| Zdroj: | Journal of NeuroInterventional Surgery. 11:853-858 |
| ISSN: | 1759-8486 1759-8478 |
| DOI: | 10.1136/neurintsurg-2018-014218 |
| Popis: | ObjectiveThis study aimed to compare the hemodynamic differences among no sac (NOS), porous media (POM) and finite element analysis (FEA) models to investigate the recurrence-related risks for coiled intracranial aneurysms (IAs).MethodsThe study enrolled 10 patients with 11 IAs who received simple coiling treatment and hemodynamic simulations were performed for all IAs using the above three models. Velocity, wall shear stress (WSS) and residual flow volume (RFV) were calculated and compared in order to assess the model differences for both aneurysm sac and parent vessel regions.ResultsFor parent artery regions, all three models produced similar flow patterns and quantification analysis did not indicate differences in velocity and WSS (p>0.05). For aneurysm sac regions, the FEA model resulted in higher sac-maximized (0.18 m/s vs 0.06 m/s) and sac-averaged velocity (0.013 m/s vs 0.007 m/s), and higher sac-averaged (0.55 Pa vs 0.36 Pa, p=0.006) and sac-maximized WSS (12.1 Pa vs 6.6 Pa) than the POM model. The differences in RFV between the POM and FEA models under 11 different isovelocity thresholds (0.0001 m/s, 0.001 m/s, 0.002 m/s, 0.005 m/s, 0.01 m/s, 0.02 m/s, 0.05 m/s, 0.1 m/s, 0.2 m/s, 0.5 m/s, and 1 m/s) showed that the POM RFV was generally larger than those of the FEA model.ConclusionsCompared with the FEA model, the POM model provides a lower velocity and WSS and higher RFV for the aneurysm sac, which could lead to incorrect estimates of the recurrent risk of coiled IAs under high packing density. |
| Databáze: | OpenAIRE |
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