Ischemic stroke associated with the use of a synthetic cannabinoid (spice)

Autor: Helge H. Müller, Caroline Lücke, Kristin Machold, Tobias Struffert, Sebastian Moeller, Stefan T. Gerner, Stefan Schwab, Bernhard Schwarze, Alexandra Philipsen, Martin Köhrmann
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Popis: Synthetic cannabinoids, i.e. "spice", are psychoactive drugs with increasing use worldwide. Spice may have harmful neuropsychiatric and physical side effects. Here, we present the case of a 25-year-old man with ischemic stroke after smoking spice on the previous evening. Diagnostic work-up was negative for other common causes of stroke. Toxicology screen unveiled the cannabimimetic ADB-FUBINACA in the drug sample and in patient's urine. The cardiac sympathomimetic effect of spice might have triggered an unnoticed episode of tachyarrhythmia and resulted in stroke via cardioembolic etiology. Thus, in absence of other risk factors, a careful patient history of spice use is recommended for patients with acute neurological deficits.
Databáze: OpenAIRE