| Autor: |
Dong, Yang, Hao, Lin, Fang, Kun, Han, Xiao-Xiao, Yu, Hui, Zhang, Jian-Jun, Long-Jun Cai, Fan, Tao, Zhang, Wen-Da, Pang, Kun, Ma, Wei-Ming, Xi-Tao Wang, Cong-Hui Han |
| Rok vydání: |
2021 |
| DOI: |
10.6084/m9.figshare.13642028.v1 |
| Popis: |
Additional file 1: Table A1. Thirty-nine components of Solanum nigrum and their corresponding molecular weight (MW), predicted oral bioavailability (OB) and drug likeness (DL) scores. Table A2. Bladder cancer (BC) related targets in Solanum nigrum. By combining the related targets of active ingredients screened from S. nigrum and the disease-related targets, 100 overlapping targets (involving 23 duplicates) were selected as the key targets involved in the treatment of BC. Table A3. Gene ontology (GO) terms of therapeutic target genes and their corresponding counts, p-value, and FDR. Through the GO enrichment of the key targets, 86 remarkably enriched (p-value ≤0.01) GO terms were obtained, indicating that some targets were involved in tumorigenesis. Table A4. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway of therapeutic target genes and their corresponding counts, p-value, and FDR. Through KEGG enrichment of the key targets, 89 remarkably enriched (p-value ≤0.01) pathways were obtained, indicating that numerous targets are involved in the processes of tumorigenesis and tumor progression. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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