Effects of transcranial direct current stimulation on grip force control in patients with cerebellar degeneration
| Autor: | Dagmar Timmann, Liane John, Joachim Hermsdörfer, Michael Küper, Thomas Hulst |
|---|---|
| Přispěvatelé: | Department of Social and Behavioural Sciences |
| Rok vydání: | 2017 |
| Předmět: |
After effects
0301 basic medicine medicine.medical_specialty Anodal tdcs Cerebellum Neurology medicine.medical_treatment Medizin Motorcortex lcsh:RC346-429 03 medical and health sciences 0302 clinical medicine Physical medicine and rehabilitation medicine Cerebellar Degeneration In patient lcsh:Neurology. Diseases of the nervous system Direct current Transcranial direct-current stimulation Research Hand held 030104 developmental biology medicine.anatomical_structure Physical therapy Neurology (clinical) Grip force Psychology 030217 neurology & neurosurgery |
| Zdroj: | Cerebellum and Ataxias, 4(1):15. BioMed Central Ltd. Cerebellum & Ataxias Cerebellum & Ataxias, Vol 4, Iss 1, Pp 1-9 (2017) |
| ISSN: | 2053-8871 |
| Popis: | Background: The control of grip forces when moving a hand held object is impaired in patients with cerebellar degeneration. We asked the question whether after-effects of anodal transcranial direct current stimulation (tDCS) applied to the lateral cerebellum or M1 improved grip force control in cerebellar patients. Methods: Grip force control while holding an object during cyclic arm movements was assessed in patients with pure cerebellar degeneration (n = 14, mean age 50.2 years ± SD 8.8 years) and age- and sex-matched control participants (n = 14, mean age 50.7 years ± SD 9.8 years). All subjects were tested before and after application of tDCS (2 mA, 22 min) in a within-subject design. Each subject received anodal tDCS applied to the cerebellum, anodal tDCS applied to M1 or sham-stimulation with a break of 1 week between the three experimental sessions. Results: There were no clear after-effects of tDCS on grip force control neither in control participants nor in cerebellar patients. Cerebellar patients showed typical impairments with higher grip forces, a higher variability of movements. Conclusion: In the present study, deficits in grip force control were neither improved by tDCS applied over the cerebellum nor M1 in cerebellar degeneration. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink