Additional file 1 of Single-cell transcriptomics reveals the effect of PD-L1/TGF-β blockade on the tumor microenvironment

Autor: Yoong Wearn Lim, Coles, Garry L., Savreet K. Sandhu, Johnson, David S., Adler, Adam S., Stone, Erica L.
Rok vydání: 2021
DOI: 10.6084/m9.figshare.14670453
Popis: Additional file 1. Supplementary figures. Figure S1. Anti-PD-L1 plus anti-TGF-β in the murine tumor model HuPD-L1-MC38. Figure S2. Anti-PD-L1 plus anti-TGF-β in the murine tumor model CT26. Figure S3. Quality control of single cell RNA-seq of anti-PD-L1 ±anti-TGF-β treated EMT6 tumor-bearing mice. Figure S4. CD45-cell analysis and InferCNV of anti-PD-L1 ±anti-TGF-β treated EMT6 tumor-bearing mice. Figure S5. scRNA-seq marker gene expression. Figure S6. scRNA-seq cell type composition and chemokine expression. Figure S7. Association of chemokine gene expression with inferred immune cell infiltration in TCGA. Figure S8. Flow cytometry-based expression of key genes in tSNE identified populations.
Databáze: OpenAIRE