Stereospecific construction of substituted piperidines. Synthesis of (−)-paroxetine and (+)-laccarin
| Autor: | John F. Bower, Thomas Riis-Johannessen, Andrew J. Whitehead, Peter Szeto, Timothy Gallagher |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Indoles
Stereochemistry Chemistry Metals and Alloys Enantioselective synthesis Stereoisomerism General Medicine General Chemistry Cleavage (embryo) Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Paroxetine Stereospecificity Piperidines Materials Chemistry Ceramics and Composites Sulfonic Acids |
| Zdroj: | Chem. Commun.. :728-730 |
| ISSN: | 1364-548X 1359-7345 |
| DOI: | 10.1039/b617260a |
| Popis: | Short and efficient enantioselective syntheses of (–)-paroxetine and (+)-laccarin are described based on the highly stereospecific cleavage of C(3)-substituted 1,3-cyclic sulfamidates. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|