Enantioselective Addition of a 2‐Alkoxycarbonyl‐1,3‐dithiane to Imines Catalyzed by a Bis(guanidino)iminophosphorane Organosuperbase

Autor:	Masafumi Oishi, Masahiro Terada, Tadahiro Takeda, Azusa Kondoh
Rok vydání:	2015
Předmět:	Addition reaction Chemistry Stereochemistry Enantioselective synthesis General Medicine General Chemistry Optically active Combinatorial chemistry Catalysis chemistry.chemical_compound Organocatalysis Organic synthesis Phosphazene Dithiane
Zdroj:	Angewandte Chemie International Edition. 54:15836-15839
ISSN:	1521-3773 1433-7851
Popis:	A chiral bis(guanidino)iminophosphorane catalyzes enantioselective addition reactions of a 1,3-dithiane derivative as a pronucleophile. The chiral uncharged organosuperbase facilitates the addition of benzyloxycarbonyl-1,3-dithiane to aromatic N-Boc-protected imines to provide optically active α-amino-1,3-dithiane derivatives, which are valuable versatile building blocks in organic synthesis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20850bf7e923ecb3c40d6e66fd31c7fe https://doi.org/10.1002/anie.201508178 Zobrazit plný text záznamu Plný text