Is a morphologically intact anal sphincter necessary for success with sacral nerve modulation in patients with faecal incontinence?
| Autor: | S. M. P. Koch, Jarno Melenhorst, W.G. van Gemert, Ö Uludag, Cor G. M. I. Baeten |
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| Přispěvatelé: | RS: NUTRIM - R2 - Gut-liver homeostasis, Algemene Heelkunde |
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Male
medicine.medical_specialty Percutaneous Lumbosacral Plexus Anal Canal Electric Stimulation Therapy Risk Assessment Severity of Illness Index Statistics Nonparametric Cohort Studies Reference Values Severity of illness medicine Humans In patient Probability Retrospective Studies business.industry Gastroenterology Retrospective cohort study Recovery of Function Electrodes Implanted Surgery Lumbosacral plexus Treatment Outcome medicine.anatomical_structure Intact anal sphincter Quality of Life Sphincter Female Implant business Fecal Incontinence Follow-Up Studies |
| Zdroj: | Colorectal Disease, 10(3), 257-262. Wiley |
| ISSN: | 1462-8910 |
| DOI: | 10.1111/j.1463-1318.2007.01375.x |
| Popis: | Objective Sacral nerve modulation (SNM) for the treatment of faecal incontinence was originally performed in patients with an intact anal sphincter or after repair of a sphincter defect. There is evidence that SNM can be performed in patients with faecal incontinence and an anal sphincter defect. Method Two groups of patients were analysed retrospectively to determine whether SNM is as effective in patients with faecal incontinence associated with an anal sphincter defect as in those with a morphologically intact anal sphincter following anal repair (AR). Patients in group A had had an AR resulting in an intact anal sphincter ring. Group B included patients with a sphincter defect which was not primarily repaired. Both groups underwent SNM. All patients had undergone a test stimulation percutaneous nerve evaluation (PNE) followed by a subchronic test over 3 weeks. If the PNE was successful, a permanent SNM electrode was implanted. Follow-up visits for the successfully permanent implanted patients were scheduled at 1, 3, 6 and 12 months and annually thereafter. Results Group A consisted of 20 (19 women) patients. Eighteen (90%) had a positive subchronic test stimulation. Twelve patients had a successful SNM implant during middle-term follow-up. Group B consisted of 20 women. The size of the defect in the anal sphincter varied between 17% and 33% of the anal circumference. Fourteen (70%) had a positive subchronic test stimulation. Twelve patients had a successful SNM implant during middle-term follow-up. In both groups, the mean number of incontinence episodes decreased significantly with SNM (test vs baseline: P = 0.0001, P = 0.0002). There was no significant difference in resting and squeeze pressures during SNM in group A, but in group B squeeze pressure had increased significantly at 24 months. Comparison of patient characteristics and outcome between groups A and B revealed no statistical differences. Conclusion A morphologically intact anal sphincter is not a prerequisite for success in the treatment of faecal incontinence with SNM. An anal sphincter defect of |
| Databáze: | OpenAIRE |
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